Small Molecule Analysis Product Guide by Matrix
Use the guide to learn more about which DPX product can be used with each sample matrix. Contact us for information on custom method development.
Matrix:
Urine
Pretreatment:
Hydrolysis
Tip-on-Tip Filtration
< 2 minutes, beta-glucuronidase enzyme removal, improved dilute and shoot
OR
Dispersive Pipette XTRaction
< 10 minutes, increased sensitivity, cleanest extract
Dilute
to desired factor*
Analysis:
LC-MS
*Depending on mass spectrometer sensitivity, solvent evaporation may be required when using dispersive pipette extraction.
Matrix:
Oral Fluid
Tip-on-Tip Solid Phase Extraction
Ideal for the most viscous oral fluid samples.
OR
Dispersive Pipette XTRaction
Ideal when using pre-filtration.
Solvent Evaporation
Analysis:
LC-MS
Matrix:
Blood/Serum
Tip-on-Tip Protein Precipitation
Benefits: < 5 minutes, preparation straight for analysis
OPTIONAL
Dispersive Pipette XTRaction
Benefits: After ToT add cleanup or SPE for specific analytes of interest prior to analysis
Analysis:
LC-MS
Hair
Meconium
Tissue
Dispersive Pipette XTRaction
Benefits: Fast, easy to use, easy to automate
Analysis:
LC-MS
Matrix:
Cannabis
Flower, extract or edibles
Tip-on-Tip Filtration
Benefits: Particulate removal down to less than 1 μm; eliminate clogging in downstream analysis
OPTIONAL
Dispersive Pipette XTRaction
Benefits: Add cleanup or SPE to remove matrix interferences